The views expressed herein do not necessarily represent the views of the Bureau of Women’s Health and Gender Analysis, Health Canada. [...] Depo Provera: The Basics Depo Provera® (depot medroxyprogesterone acetaMteP [AD]) was developed by the Upjohn Company (now part of Pfizer) in the late 01’9s5, and first approved for the treatment of endometriosis, and threatened or uhalb mit iscarriage in 1960 (however, in 1974 it was shown to be ineffective for these puserpso)2. [...] Depo Provera and the Food and Drug Administration (FDA): the U. S. experience Depo Provera was initially approved for contracveep tuise in the United States in 1974. [...] The actions of the Coalition brought the questifo rne ogulatory approval of drugs into both the public and the political domains. [...] Although criticse nidtify BMD loss as a major public health concern, others including Anwd rKeaunitz, author of one of the key studies64 that prompted the FDA and Health Canada advis,o sreiees the potential decline in Depo use as the public health concern.