cover image: 2009 pandemic influenza A (H1N1) vaccine : Vaccin contre la grippe pandemique A (H1N1) 2009

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2009 pandemic influenza A (H1N1) vaccine : Vaccin contre la grippe pandemique A (H1N1) 2009

16 May 2011

First, the pH1N1 virus was per dose compared to unadjuvanted vaccines to produce the same level of criteria, include the proportion of injected into the fluid surrounding the embryo of fertilized hens’ eggs immune response) (16). [...] Approval for use of research (related to both adjuvanted As per the U. S. Food and Drug the AS03-adjuvanted pH1N1 vac- and unadjuvanted formulations) Administration (FDA) guidelines, cine was granted by Health Canada published since the start of the the recommended serum HI anti- on October 21, 2009 (7), and the pH1N1 pandemic and to contextu- body response profile for pandemic unadjuvanted pH1N1 [...] A German study (N=45,733) also children and adolescents (9 to 17 A note of caution is warranted due using the AS03-adjuvanted pH1N1 years old), adults (18 to 60 years to the lack of standardization of vaccine found very high estimates old), and older adults (>60 years the hemagglutination inhibition of VE in adults (i.e. [...] Centre de collaboration nationale des maladies infectieuses 3 a reasonable cost, despite the fact The occurrence of rare sequelae is cination campaigns that took place that the mass campaign began after inevitable when a vaccine is ad- in the fall of 2009, it was lower than the first wave of the pandemic (37). [...] The response within three weeks after a with the pH1N1 vaccine lay within number of observed GBS cases ap- single dose of unadjuvanted pH1N1 the expected safety profile for com- peared to be lower than the number vaccine containing 15 µg of HA mon events with seasonal influenza of expected GBS cases, suggesting (49).
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Authors

Wong, Kenny

Pages
12
Published in
Canada

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